Session Title: Essential cellular factor(s) for human sapovirus propagation

Oral Abstracts: 

• Development of an ex vivo model to study the zoonotic transmission of noroviruses
  • Nele Villabruna, University of Veterinary Medicine Hanover
• Dysregulated innate epithelial response to norovirus infection in intestinal organoids from patients with common variable immunodeficiency
  • Magdalena Neijd, Linköping University, Sweden
• Human Norovirus Replicates in Hepatocytes and Other Liver Cells in Zebrafish Larvae    
  • Lorane Molineaux, KU Leuven

Oral Abstracts: 

• Intercellular calcium waves are a conserved feature of enteric virus infection and drive Tulane virus spread
  • Joseph Hyser, Baylor College of Medicine
• Norovirus alters host metabolism for efficient virus replication
  • Adam Hafner, University of Michigan
• Overcoming host restriction to enable continuous passaging of human noroviruses in human intestinal enteroids
  • Gurpreet Kaur, Baylor College of Medicine
• Single-cell transcriptomic analysis of duodenal biopsies and enteroids from immunocompromised patients with chronic norovirus infection
  • Yuki Matsushima, Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health - VIRTUAL PRESENTATION
• Identification of a Cellular Host Factor Required for Human Sapovirus Infection
  • Kei Haga, Kitasato University

All posters to be set up on the 2nd floor of the Kinnear Centre. Posters can be left up until Wednesday afternoon. 

Odd numbered posters will present on Monday, even numbered posters will present on Tuesday. 

Session Title: Norovirus pathogenesis: from cell death to transmission

Session Chairs:
Christiane Wobus
Sasirekha Ramani

Oral Abstracts:

• Mutational Analysis of Human Norovirus VP2 Elucidates Critical Molecular Interactions for Virus Assembly
  • Sue Crawford, Baylor College of Medicine
• Structural studies of the calcivirus entry pathway – conformational flexibility as a marker of virulence?
  • David Bhella, MRC - University of Glasgow Centre for Virus Research
• Structure of the Norovirus NTPase
  • Daniel Hurdiss, Utrecht University

Session Title: Metagenomics for Norovirus: From Detection to Genotype-Phenotype Insights

Session Chair: Joana Rocha Pereira

Oral Abstracts: 

• CRISPR-Cas13a Coupled with a Capsid Integrity Assay for Detecting Norovirus in Food
  • Axel Ossio, Universidad Autonoma de Nuevo Leon
• Evaluation of sensitivity and specificity of New Immunochromatograpghy (IC) kit for the rapid detection of norovirus associated acute gastroenteritis in Dhaka, Bangladesh
  • Shuvra Kanti Dey, Jahangirnagar University

Odd numbered posters will present during this poster session.

Session Title: Proteomics as a complementary approach to measure norovirus infection in clinical samples

Session Chairs:
Janet Mans
Vernon Ward

Oral Abstracts: 

• Burden of viral pathogens causing acute gastroenteritis in children less than 2 years of age in a U.S. birth cohort
  • Jennifer Cannon, CDC Foundation
• Comparing Norovirus Gastroenteritis in Medically-Attended Patients and Community-Cohort in Central Wisconsin, United States
  • Joshua Petrie, Marshfield Clinic Research Institute
• Gastrointestinal viral Infection in Adult and Pediatric Solid Organ Transplant Recipient: A Retrospective, Single-center Study from 2015 to 2022
• Norovirus and Sapovirus Associated Chronic Diarrhea in SOT: Does Viral Load Correlate with Severity of Symptoms?
  • Varalika Tyagi, University of Alberta - VIRTUAL PRESENTATION

Oral Abstracts: 

• Human milk oligosaccharides and norovirus GII gastroenteritis in a Nicaraguan birth cohort
  • Rebecca Rubinstein, University of North Carolina at Chapel Hilll
• Molecular Characterization of Human Noroviruses among Children with Acute Gastroenteritis in Ebonyi State, Nigeria
  • Olumuyiwa Babalola Salu, College of Medicine, University of Lagos
• Norovirus Shedding in Symptomatic and Asymptomatic Patients: Insights from a Tertiary Care Hospital-Based Study in Bangladesh
  • Syed Moinuddin Satter, icddr,b
• Sporadic, Medically Attended Norovirus Infection in the United States, 2023-2024
  • Mark Schmidt, Kaiser Permanente Center for Health Research

Session Title: Using murine norovirus to decipher mechanisms of adaptive immune control

Session Chair: Tomoichiro Oka

All members of the Scientific Committee to meet in room 202 for a lunch meeting. 

Session Title: The saga to monitor and control norovirus: the rise and fall of variants

Virtual Presentation

Session Chairs:
Tulio Fumian
Jan Vinjé

Oral Abstracts: 

• Characterization of Binding and Antigenic Properties in Emerging GII.17 Norovirus Variants
  • Francisco Morais Esteves, Erasmus MC
• Characterization of human norovirus and host genetic susceptibility profiling in South African children with gastroenteritis
  • Ronewa Khumela, University of Pretoria
• Dynamics of asymptomatic Norovirus infections in a three-year cohort of children from rural communities in Ecuador
  • Rommel Guevara, Universidad San Francisco de Quito
• Emergence of GII.3 as most prevalent norovirus strain among infants and children with acute gastroenteritis in Bangladesh
  • Shuvra Kanti Dey, Jahangirnagar University

Oral Abstracts: 

• Genotypic distribution and molecular epidemiology of norovirus among under-five children hospitalized with acute gastroenteritis in South India, 2005-2020
  • Tintu Varghese, Christian Medical College Vellore
• Global trends in norovirus genotype distribution among children with acute gastroenteritis captured by NoroSurv, 2020-2025
  • Jennifer Cannon, CDC Foundation
• Increased norovirus activity associated with the emergence of GII.17[P17] in season 2023/24 in Germany
  • Sandra Niendorf, Robert Koch Institute
• Molecular Characterization and Isolation of Contemporary Porcine Sapoviruses from Swine Farms in the United States
  • Qiuhong Wang, The Ohio State University
• Screening Norovirus Genetic Diversity in Public Datasets using Aitne, a Novel Open Source Genotyper
  • Dennis Schmitz, Erasmus Medical Center / Netherlands Institute of Public Health and the Environment (RIVM)

Even numbered posters will present today. 

Session Title: Immunity in HuNoV Vaccine Trials: Answers to Old Questions and Asking New Ones

Session Chairs: 
Ben Lopman
Miranda de Graaf

Oral Abstracts: 

• Antigenic characterization of human noroviruses reveals limited cross-blocking between genotypes
  • Lauren Ford-Siltz, Food and Drug Administration
• Efficacy, safety, immunogenicity, and cross-reactivity of intramuscular HIL-214 norovirus vaccine in healthy children 5 Months of age at initial vaccination
  • Michael Abram, Robert Hershberg, HilleVax
• Milk IgAs of early life origin B cells have cross-neutralizing antiviral properties
  • Hannah Karen Labayo, NIH-NHLBI
• Next Generation Oral Norovirus Vaccine Candidate Generates Improved Immune Responses to GI.I and GII.4 strains in Humans
  • Sean N. Tucker, Vaxart, Inc.

Oral Abstracts: 

• Neutralizing antibody responses to GII.4 vaccination from early childhood through old age: harnessing the power of immune imprinting to drive breadth
  • Lisa Lindesmith, University of North Carolina-Chapel Hill
• Safety and Immunogenicity of mRNA-1403, a Multivalent Norovirus mRNA Vaccine, in Healthy Adults: Interim Results of a Phase 1/2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Trial
  • Meklit Workneh, Moderna
• Targeting the Gut: Oral Norovirus Vaccine Generates Protective Mucosal Immunity and Reduces Viral Shedding Following GI.1 Challenge
  • Becca Flitter, Vaxart
• Repertoire of naturally acquired norovirus maternal antibodies in newborns
  • Verónica Costantini, Centers for Disease Control and Prevention

Session Title: Enteric Viruses in Food Systems: From Occurrence to Control 

Session Chairs:
Joanne Hewitt
Soizick Leguyader

Oral Abstracts: 

• Direct comparison of the persistence of infectious human norovirus and its cultivable surrogate, hepatitis A virus, on frozen raspberries
  • Émilie Larocque, Canadian Food Inspection Agency
• The final straw: berries and viruses
  • Malak Esseili, University of Georgia
• Challenges in the culture of norovirus isolated from oyster tissues
  • Marion Desdouits, Ifremer

Session Chairs:
Bonita Lee
Marion Koopmans

Session Title: Capture-based metaviromics to describe caliviridae diversity in contaminated shellfish

Oral Abstracts: 

• Wastewater-based epidemiology at a global scale for norovirus surveillance: From metagenomics to phenotypical characterization
  • Ray William Izquierdo Lara, Erasmus MC
• Wastewater-based Surveillance of Norovirus and Sapovirus from 2020 - 2024 in Alberta, Canada
  • Judy Qiu, Alberta Public Health Laboratory/University of Alberta

Shuttles depart the Banff Centre at 5:45pm.

Session Chairs:
Kim Green
Jason MacKenzie

Oral Abstracts:

• VIRTUAL PRESENTATION: Development of Reporter Replicon Systems for Genogroup II Human Noroviruses: Tools for Antiviral Screening and Mechanistic Insight & Evaluation of MMV Pandemic Response Box compounds identifies MMP-inhibitor against HuNoV replication
  • Myra Hosmillo, University of Cambridge
• Oral Direct-Acting Antiviral CDI-988 for norovirus infection prevention and treatment: Mechanism of Action and Phase 1 Study Results
  • Sam Lee, Cocrystal Pharma Inc.
• Polyamine depletion inhibits norovirus infection and blocks virus-induced apoptosis
  • Stefan Taube, University of Lübeck
• Targeting calicivirus entry – a VP2 peptide inhibitor of Feline Calicivirus
  • Charlotte Lewis, University of Glasgow Centre for Virus Research